Research is part of the project FSRG-2020-0014 вЂњArctic Genomics: epidemiology, heredity and pathologyвЂќ.ДЄ.I. The prevalence of congenital malformations is vary at approximate intervals of 4-5 years and increase tendency may persist for several years because improved diagnostic methods. Congenital malformations prevalenceД¬onclusion: Thus, Yakutia is region with a high frequency of congenital malformations, and in recent years an increase the frequency of their registration. The observed differences are statistically significantly (p < 0.05).

The high frequencies of malformations in 2012, 20 was observing (Table 1). At this period, the average annual number of births was 15725.7 (SD 1174.3). Results: The incidence rate of congenital malformations over a 12-year period averaged 29.4 cases per 1000 newborns with a standard deviation of 2.9. Material and methods: The data from Medical Genetic Center Register was analyzing by the MedCalc 15.8 program. The purpose of epidemiological monitoring is to improve the prevention and treatment of congenital malformations. In Yakutia, the prevalence of congenital malformations is recording in Register of Medical Genetic Center, Republican Hospital в„–1 - вЂњNational Medical CenterвЂќ. Introduction: Congenital malformations represent an urgent problem that affects the structure of infant and child mortality. Ammosov North-Eastern Federal University, Yakutsk, Russian Federation, 2Medical Genetic Center, Republican Hospital в„–1 вЂ“ вЂњNational Medical CenterвЂќ, Yakutsk, Russian Federation Maksimova 1 1Research Laboratory вЂњMolecular Medicine and Human GeneticsвЂќ, Medical Institute, M. E-P01 Reproductive Genetics/Prenatal GeneticsД®-P01.07 Epidemiological monitoring of congenital malformations in Yakutia from 2007 to 2018 A.

Long war gene mods